Major Bill Cage is an officer who has never seen a day of combat when he is unceremoniously demoted and dropped into combat. Cage is killed within minutes, managing to take an alpha alien down with him. He awakens back at the beginning of the same day and is forced to fight and die again... and again - as physical contact with the alien has thrown him into a time loop.

A successful lawyer, with a new wife and infant, agrees to care for his teenage son from a previous marriage after his ex becomes concerned about the boy's wayward behavior.

After finding a host body in investigative reporter Eddie Brock, the alien symbiote must face a new enemy, Carnage, the alter ego of serial killer Cletus Kasady.